The Mavericks lead the Sun Belt with 318 runs scored this season.
UTA's 26 wins are the most in a season under third-year coach Kristie Fox.
Sam Montes threw UTA's first no-hitter since 2013 in Game 1.
UTA and South Alabama conclude the series on Saturday at 1 p.m.
Mallory Foster hit her fourth home run of the last three games in the win.