Sandra Mendoza is second in UTA single-season history with 50 runs, behind teammate Nina Villanueva.
The Mavs and Ragin' Cajuns conclude the three-game series on Saturday with a doubleheader on ESPN3.
Mya Anderson had three hits and four RBI to lead the Mavericks on Thursday.
Shelbi Sikes had a team-high eight RBI in two games, notching a career-high six in the first game.
UTA has one returning pitcher to its squad of four this season in sophomore Brittany May.