The Mavericks have won their last seven meetings with the Cardinals, dating back to 1986.
Sandra Mendoza recorded two of the four Mavericks hits, pushing her hit-streak to 17 games, matching a career-high.
The Mavs and Panthers are back in action on Sunday for the rubber match. First pitch of the is scheduled for 11 a.m. CT.
The Mavs sit 40th in the nation and second in the Sun Belt in winning percentage at .692.
Sandra Mendoza was 6-for-10 with three runs, and an RBI to hit .600 on the weekend.